What Is Hypereosinophilic Syndrome?
Peripheral blood eosinophilia> 1500 / l for 6 months or more; no parasitic, allergic, or other causes of eosinophilia were found on examination; clinical manifestations of organ system involvement or abnormal function were directly related to eosinophilia . Idiopathic hypereosinophilic syndrome is a group of unexplained eosinophilic diseases, including eosinophilic endocarditis.
Idiopathic eosinophilia syndrome
- Peripheral blood
- Idiopathic eosinophilia syndrome
- Idiopathic eosinophilia syndrome
- Clinical manifestations are diverse, and may include fever, cough, chest pain, palpitations, shortness of breath, neuropsychiatric symptoms, pruritus, rash, enlarged liver, spleen and lymph nodes, and edema at the extremities. The most serious are subendocardial thrombosis and fibrosis, and chordae fibrosis, which leads to atrioventricular valve reflux and eventually congestive heart failure. Echocardiography can be used for diagnosis and monitoring. Embolism from the heart, diffuse encephalopathy, peripheral neuropathy, and especially polymononeuritis are the main manifestations of nervous system involvement. The skin, respiratory system, and digestive system are also frequently affected, and those with major organ involvement have a poor prognosis. Those with angioedema show that the heart is often not involved and the prognosis is good.
Idiopathic eosinophilia syndrome
- Common diagnosis
- Idiopathic eosinophilic syndrome (IHES)
- In 1975, the diagnostic criteria for IHES proposed by Chusid et al. Are still commonly used in clinical practice:
- Because the disease is caused by eosinophil-infiltrated tissue or the release of eosinophilic contents, treatment should try to reduce the eosinophil count. It is not necessary to treat before the progress of dysfunction of the sexual organ system, the patient every 3 to 6 Make a general check once a month. Complications of the organ system should be actively treated.
- Idiopathic eosinophilia syndrome
- Prevention: The main measures are to strengthen the prevention and treatment of the induced causes to prevent the occurrence and progression of the disease. Prognosis: The prognosis of eosinophilia caused by various reasons is very different. It is necessary to identify the disease with poor prognosis and eosinophilia. IHES patients were untreated, 50% died within 1 year, and the average survival was 9 months. Since the 1980s, the 5-year survival rate of using hormones and cytotoxic drugs has been 20% to 80%.
- Idiopathic eosinophilia syndrome
- 1. The common complication is that heart disease becomes myocardial endometrial thrombosis and fibrotic chordae fibrosis, which leads to progressive congestive heart failure in the atrioventricular valve regurgitation. The echocardiogram can be used for diagnosis and monitoring. Nervous system affected by emboli, diffuse encephalopathy, and peripheral nerves