What Is Neonatal Syphilis?

Congenital syphilis, also known as fetal syphilis, is syphilis caused by Treponema pallidum from the mother through the placenta into the fetal blood circulation. Congenital syphilis should be paid great attention by pediatric clinicians.

Neonatal congenital syphilis

Neonatal congenital syphilis has various clinical manifestations, lacks specificity in symptoms and signs, and can affect multiple organs at the same time.

Penicillin is the most effective drug for treating syphilis. For children without serious complications, the clinical cure rate is nearly 100%. 2nd, 4th, 6th, 9th, 12th after antiviral treatment

Serum examination (RPR) and follow-up are required for one month. Those who do not decrease or increase in RPR titer should be given regular treatment again. The follow-up of this case shows that the early diagnosis after birth of congenital syphilis, and those who are fully treated with penicillin have a good prognosis.

In the severe situation where the incidence of syphilis is increasing, congenital syphilis should be paid great attention by pediatric clinicians. A prominent problem in the prevention and treatment of congenital syphilis is the failure to detect pregnant women with syphilis in a timely manner, and even to prevent regular systemic treatment during pregnancy. Therefore, strengthening education and carrying out syphilis testing during pregnancy, early diagnosis, and regular treatment are effective ways to reduce the incidence and mortality of congenital syphilis.