What Is Pharmacoepidemiology?
Pharmacoepidemiology is an applied science that uses the principles and methods of epidemiology to study drug use and its effects in a population.
Pharmacoepidemiology
(Medical Science)
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- Chinese name
- Pharmacoepidemiology
- Pharmacoepidemiology is an applied science that uses the principles and methods of epidemiology to study drug use and its effects in a population.
- Drug utilization and distribution of drug effects in the population; The ultimate goal of the study is to provide medical units, preventive health departments, pharmaceutical administrations, and the general public with information on drug utilization and the safety and effectiveness of drugs in the population, and to propose rational drug use Favorable opinions and suggestions to make the development, production, operation, management and use of drugs more reasonable.
- The focus of work is to develop and improve the adverse drug reaction (ADR) surveillance in depth and breadth.
- (1) Descriptive research method, to study the distribution of adverse reactions in a certain group of people after medication, through comparison and analysis, suggest a certain possibility, and lay the foundation for further research.
- (2) Analytical research methods, including case-control studies and cohort studies.
- 1) Case-control studies, also known as retrospective studies, are one of the main methods of post-marketing research.
- 2) Cohort study, also known as cohort study or cohort study, among those who are not suffering from the disease to be studied, the people exposed to a drug are used as the exposure group, and those not exposed to a drug are used as the control group. Incidence or test attributable risk.
- (3) Experimental research methods
- 1) Randomized controlled clinical trials. Patients are randomly divided into a test group and a control group. The control group is given a placebo or a reference treatment, and then the effect of the drug is evaluated. The medical education network collects and organizes clinical trials. Special attention should be paid to random, controlled and blind treatment.
- 2) Community experiments are mainly crowd intervention trials.
- (1) The sample is larger and the data estimation is more accurate;
- (2) Can be carried out for a long time;
- (3) Can be performed in special groups;
- (4) The effects of other diseases and other drugs on drug effects can be studied;
- (5) Research on drug application can be carried out;
- (6) Study on the influence of overdose on human body;
- (7) Pharmacoeconomic studies can be conducted.