What is an adenocarcinoma signet ring?

in adenocarcinoma signet, skin cells from internal organs lining their structure and are unsuitable for their intended purpose. These cells are quickly reproduced and combined to form cancer growth. This form of cancer usually affects the organs of the digestive system, but theoretically, signet circular cells in any organ that is lined with epithelium may occur. Adenocarcinoma of this type is rare but very aggressive.

The special physical appearance of individual cancer cells gives the signet adenocarcinoma its name. Normally, a part of the cell is placed in the center of the cell, which contains deoxyribonucleic acid (DNA) necessary for reproduction. In the circular cells of the Signet, this structure, which is called the core, outside the center and suspended in mucus. The resulting structure is similar to the Emblems rings, which are traditionally used by a royal rank.

The presentation of adenocarcinoma signet is identical to the more common cancer of the same organ. In stomach cancer, these symptoms mOhou include bowel pain, stomach and bloody stools. Although this condition is extremely rare, it can affect the lungs. In these cases, persistent cough, chest pain and bloody mucus are often reported.

diagnosis of adenocarcinoma of signet is generally performed by a combination of blood tests and diagnostic imaging. The abnormal number of blood cells may indicate the presence of cancer and the patient's symptoms may provide guides for its location, but the accurate position of abnormal growth requires ultrasound, X -ray or magnetic resonance (MRI). If a tumor is found, the surgeon usually takes a small sample of growth in the procedure called biopsy. The visual confirmation of the circular cells of the Signet occurs by exploring the tissue under the microscope.

Depending on the affected area, surgical removal of cancer growth may be necessary. Although radiation treatment may be a king before surgeryTCE used, postoperative radiation therapy is usually not recommended. Due to the aggressive nature of signet adenocarcinoma, chemotherapy is almost always prescribed.

Often, the cancer of the signet circle of the lower digestive tract is treated with a special type of chemotherapy called hypertermic intraperitoneal chemotherapy (HIPEC). After removal of any tumors in the stomach, chemotherapeutic drugs are heated to slightly above the normal body temperature and pass through the abdominal cavity. In many cases, localized drugs of drugs may reduce the systematic side effects of traditional chemotherapy.

The prognosis for patients suffering from adenocarcinoma signet is generally poor. Historically, the disease is very aggressive and often spreads to other areas of the body before diagnosis. In addition, cancer usually does not respond to chemotherapy.

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