What are the killers of pain?

painkillers are medicines designed specifically to alleviate pain. Pharmaceutical companies are usually created and sold to painkillers. While some painkillers have specific health purposes, as well as some migraine formulations, most painkillers are a general purpose.

There are several ways in which painkillers are categorized. One of the methods is to divide them into pain medications through the counter (OTC) - those that the consumer can buy without a prescription - and those that require a regulation for legal purchase.

The second way to categorize painkillers is their chemical type. Painkillers include opiates-such as narcotics: conventional or non-selective, semi-sective and selective non-steroidal anti-inflammatory drugs (NSAIDs); painkillers that do not fit into any of these categories; and combined painkillers. Two things to be aware of: Food and drug management do not report semi -semi-AID and selective NSAIDs are also called COX-2S inhibitor. Here are some of the most famous painkillers in each category:

6 Non -selective nsaids aspirin, ibuprofen, naproxen Selective NSAIDS Celebrex® and VIOXX® none of the above

Opiates were among the first painkillers that were discovered. Opium was cultivated by Asses, Babylonia, Egyptians and Sumerians about 3400 ° C. It was used in the 5th century B.C. Greece doctor Hippocrates, along with Salacin from Willow Bark, who is the forerunner of aspirin, which was created by German chemist Felix Hoffman in 1897. Germany of the nineteenth century was a discovery of acetaminophene. In 1889, a German scientist CharlesL Morner, found that acetaminophen was produced by the human body because it metabolized phenoty, a French discovery of painkillers.

But until the twentieth centuries, Nsaids was discovered. Indomethacin, the first NSAID to be found, was found in the 60s of the 20th century by American chemist Tsung-Eying Shen. COX-2 inhibitors were discovered by American professor W. L. Xie and colleagues in 1991.