What is Regenerative Medicine?

Regenerative medicine refers to the use of biological and engineering theoretical methods to create lost or functionally damaged tissues and organs, so that they have the normal tissues and organs' mechanisms and functions.

Regenerative medicine refers to the use of biological and engineering theoretical methods to create lost or functionally damaged tissues and organs, so that they have the normal tissues and organs' mechanisms and functions.
Chinese name
Regenerative Medicine
Foreign name
regenerative medicine
Pinyin
zai sheng yi xue
Research object
Normal tissue characteristics and functions of the body
Purpose
Promote self-healing and regeneration
Concept classification
Broad and narrow sense

Regenerative medicine concept

The concept of regenerative medicine can be broad and narrow.
In a broad sense, regenerative medicine originally refers to the theory, technology, and surgical operations of tissue regeneration in the body. It can also be considered as a discipline that studies how to promote the physiological repair of trauma and tissue and organ defects, and how to perform tissue and organ regeneration and functional reconstruction. Understand that by studying the body's normal tissue characteristics and functions, trauma repair and regeneration mechanisms, and stem cell differentiation mechanisms, find effective biological treatments to promote the body's self-repair and regeneration, or build new tissues and organs to maintain, repair, regenerate or Improve the function of damaged tissues and organs.
In a narrow sense, it is a new discipline that applies the principles and methods of life sciences, materials science, clinical medicine, computer science, and engineering to research and develop theories and technologies for replacing, repairing, reconstructing, or regenerating various tissues and organs in the human body. Cross-cutting frontiers.
Regenerative medicine marks a new era for medicine to rebuild, regenerate, "manufacture", and replace tissues and organs. It also brings new hope for most medical problems facing humans, such as cardiovascular disease, autoimmune diseases, diabetes , Malignant tumors, Alzheimer's disease, Parkinson's disease, congenital genetic defects and other diseases and the treatment of various tissue and organ damage. The connotation of regenerative medicine has been expanding, including tissue engineering, cell and cytokine therapy, gene therapy and micro-ecological therapy. The International Regenerative Medicine Foundation (IFRM) has clearly identified tissue engineering as a branch of regenerative medicine. With the expansion of the concept of tissue engineering, all methods and technologies that can guide tissue regeneration are included in the category of tissue engineering, so in general, there is no strict distinction between tissue engineering and regenerative medicine.

Exploration of Regenerative Medicine

At present, the three major strategies being explored in the field of regenerative medicine include: replacing damaged tissues by transplanting cell suspensions or polymers; implantation of laboratory-produced biological artificial tissues or organs that can replace natural tissues; and through drug means Regeneration induction was performed on the damaged tissue part. However, no one strategy has yet achieved completely satisfactory results.

Regenerative Medicine Reference Materials

[1] DL Stockham. Strategies for Regenerative Medicine. Translated by Pang Xining et al. Regenerative Biology and Regenerative Medicine. First Edition, Beijing: Science Press, 2013, p14-22.
[2] Edited by Pei Xuetao. Theory and Technology of Regenerative Medicine. 1st edition, Beijing: Science Press, 2010

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