What are the effects of aromatase inhibitors on breast cancer?
aromatase inhibitors are chemicals that block aromatase production, an enzyme that stimulates estrogen production in menopause women. Some types of cancer cells use estrogen. The effects of aromatase inhibitors on breast cancer can be observed with a reduced amount of estrogen produced by a process known as aromatization, and many doctors recommend hormonal therapy aromatase after surgery or radiation to reduce the chances of returning positive estrogen-receptor breast cancer.
As soon as the woman went through menopause, her ovaries naturally produce estrogen. Some types of breast cancer cells are dependent on hormonal estrogen growth, and therefore women who have already reproached aromatase inhibitors may take to block the production of hormone and possibly reduce the chance of cancer cells in growth or spread. These effects of inhibitors of aromatase on breast cancer are usual these effects of aromatase inhibitors on breast cancer effective only for women having hormonal recipeR positive breast cancer, which is in the early stages of development.
Inhibitors of aromatase on breast cancer also bring positive results in some women who have metastatic breast cancer, repeating breast cancer positive on estrogen, as well as women diagnosed with ovarian cancer or endometriosis. The effects of aromatase inhibitors are usually evident in women who have undergone surgery to remove tumors or cancer tissue or are completed. Aromatase inhibitors are part of adjuvant hormonal therapy recommended doctors for some women, which will reduce the risk of cancer return. The Okolog usually prescribes the use of tamoxifen, another type of anti -skeleton therapy, for two to five years and then an inhibitor of aromatase for the next two to five years. Aromatase inhibitors can also be accepted after the initial round of cancer treatment.
as with most summerThere are some side effects of using aromatase inhibitors on breast cancer. This type of hormonal therapy can cause osteoporosis and bone thinning to remove estrogen from the body. Miles of heat, joint pain and fatigue are commonly associated with the use of aromatase inhibitors. Some woman experiences diarrhea, constipation and even nausea.
There are no studies that show long -term effects of aromatase inhibitors, so women should consult with their doctors about related risks. Aromatase inhibitors are also much more expensive than tamoxifen, which has a general form. Anastrozole, Exemestan and Letrozole are chemical names of three available inhibitors.