Why is bacterial resistance to ampicillin concerned?
ampicillin is an antibiotic in the family of penicillin, which was one of its class to work against a wide range of bacteria and has been used since 1961. It works by penetrating the defense of bacteria and inhibiting the production of the vital enzyme needed during the replication process. In recent years, resistance to ampicillin has developed between different bacteria due to many years of human application and extensive use in animals. Resistance to ampicillin is a reason for concern because it makes the treatment of these bacteria more difficult. In some cases, bacteria tribes may develop resistance to multiple antibiotics, which is very dangerous and almost impossible to erad. In 1927, Penicillin was the first discovered antibiotic or antimicrobial and antimicrobial and antimicrobial way and in the age of 20. Ampicillin, introduced in 1961, belongs to the same family Drugs. It works by entering bacteria through its outer membrane and preventing it from creating the necessary enzyme for a replication PRoes. Without this enzyme, bacteria are not able to complete the synthesis of the cell wall it needs to survive.
As time has passed, many bacteria strains have developed resistance to ampicillin, creating a potentially dangerous situation. There are several identified causes for this phenomenon. One of them is the overuse of antibiotics in general, leading to a larger number of bacteria that are tolerant of the presence of antimicrobials because they must adapt to survival. Resistance to older antibiotics, such as ampicillin, can develop simply because it was much longer in circulation, and there was a sufficient opportunity for bacteria to adapt.
The fact that ampicillin is very used in animal feed is particularly concerned. This caused several bacteria transmitted by foods that are also able to infect people and cause the disease to develop resistance to ampicillin. ForThe ways of these bacteria include E.Coli and Salmonella. These bacteria developed a gene for ampicillin resistance, which can be transferred from one to the other by a process called horizontal transmission, which allows the propagation of the problem. The existence in food supply is the path for rapid spread of bacteria that have resistance to ampicillin to a large amount of human population.
Resistance to ampicillin is a reason for concern because it makes it difficult to treat bacteria. A long and expensive course of treatment by a combination of drugs is often necessary to clean up infections of resistant bacteria. Another danger is that bacteria will develop resistance to multiple antibiotics. This may be particularly dangerous because bacteria are progressively difficult to treat as a census develops L antibiotic resistance. Some of these "super bacteria" are deadly and almost impossible to eliminate, a path that often begins with ampicillin resistance.