How Does the Immune System Use Basophils?

Leukocytes are a type of cells in the blood. When germs invade the human body, they can pass through the capillary wall through deformation and concentrate on the invasion site of germs, enclosing and engulfing them. If the number of white blood cells in the body is higher than normal, it is likely that the body has inflammation. Normally mature white blood cells in the human body can be divided into five categories: neutrophils, eosinophils, basophils, lymphocytes and monocytes.

Basic Information

Chinese name: Basophils

Meaning: Certain allergic diseases, blood diseases, tumors, etc.

Clinical significance of basophils

Increase

(1) Allergic diseases Allergic colitis, drugs, food, inhalation hypersensitivity, erythema and rheumatoid arthritis can increase the number of basophils.

(2) Chronic myelogenous leukemia, bone marrow fibrosis, basophil myeloid leukemia, chronic metastatic cancer, and Hodgkin's disease are often accompanied by an increase in the number of basophils. In addition, chronic hemolysis and splenectomy also showed an increase in the number of basophils.

(3) The number of basophils increases in malignant tumors, especially metastatic cancer, and the mechanism is unclear.

(4) Others such as diabetes and infectious diseases such as chicken pox, influenza, smallpox, tuberculosis, etc., can see an increase in the number of basophils.

2. reduce

The reference value of basophils in peripheral blood is very low, so its reduction is not clinically significant.