What Are Dental Pulp Stem Cells?
Pulp tissue is located in the pulp cavity inside the tooth and is the only soft tissue in the dental tissue. In 2000, Gronthos et al. Studied human dental pulp cells and found a cell that has an extremely similar immune phenotype and the ability to form mineralized nodules as bone marrow mesenchymal stem cells. The cells are fusiform and self-renew And multi-directional differentiation, has strong cloning ability. These fibroblasts isolated from dental pulp tissue are called dental pulp stem cells (Dental Pulp Stem Cells, DPSCs).
Dental pulp stem cells
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Pulp tissue is located in the pulp cavity inside the tooth and is the only soft tissue in the dental tissue. In 2000, Gronthos et al. Studied human dental pulp cells and found a cell that has an extremely similar immune phenotype and the ability to form mineralized nodules as bone marrow mesenchymal stem cells. The cells are fusiform and self-renewing. And multi-directional differentiation, has strong cloning ability. These fibroblasts isolated from dental pulp tissue are called dental pulp stem cells (Dental Pulp Stem Cells, DPSCs).
Pulp tissue is located in the pulp cavity inside the tooth and is the only soft tissue in the dental tissue. In 2000, Gronthos et al. Studied human dental pulp cells and found a cell that has an extremely similar immune phenotype and the ability to form mineralized nodules as bone marrow mesenchymal stem cells. The cells are fusiform and self-renewing. And multi-directional differentiation, has strong cloning ability. These fibroblasts isolated from dental pulp tissue are called dental pulp stem cells (Dental Pulp Stem Cells, DPSCs). |
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Dental pulp stem cells have the potential for multi-directional differentiation. In addition to cells that can form mineralized nodules, they can be differentiated into fat, bone, cartilage, muscle, vascular endothelium, liver, and nerve cells after being induced by different cytokines Department type. |
Dental pulp stem cells have the following advantages: 1. Rich sources. The naturally lost teeth of children 6-11 years old and the wisdom teeth that adults need to extract are rich in dental pulp stem cells. 2, small side effects. Dental pulp stem cells are a type of mesenchymal stem cells. They have the generality of mesenchymal stem cells, not only have low immunogenicity, they can be used without strict pairing, they will not cause strong rejection reactions, and they also have immunomodulatory functions. The foreign body has never caused rejection. 3. No ethical dispute. Because dental pulp stem cells are taken from children's naturally lost teeth and adult wisdom teeth, they are waste products and do not harm life. There is no ethical dispute. |
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