What are the cells of granulosa?
granulos cells are blocks that form a barrier around the developing follicles of oocytes inside the ovary. As follicles ripen, granulosa cells multiply to create many layers around the oocyte. Before ovulating cells, they produce estrogen, which is then excreted into the bloodstream. After ovulation, these cells become granulose cells and primarily produce progesterone. Progesterone maintains the uterus ready for egg implantation and maintains pregnancy if fertilization occurs. Many oocytes begin the maturation process at the beginning of the menstrual cycle, but the process usually only completes one. The hormone stimulating follicles (FSH) indicates oocyte to start the primary phase of the follicle. Oocytes at this stage have only one layer of these cells that surround them.
When granulosis cells form multilayer around oocyte this is referred to as the secondary phase of the follicle. Cells outside the follicle are separated to the cells of theca internal and theca externa before oocyte progresses to the tertiary stage, also calledAneé Graafia follicle. Soon after reaching the tertiary stage, the follicle will tear and relax oocyte to pass through the fallopian tube into the uterus. At this stage, oocyte will have a granulos cell layer connected by the Radiata corona.
The remaining granulos cells of the cracked follicle form corpus luteum. This structure excludes progesterone necessary to maintain pregnancy only after the first trimester. If there is no pregnancy, Corpus Luteum deteriorates to a small fibrous scar called Corpus Albicans.
The primary purpose of granulosa cells is to provide nutrients to oocyte. Sometimes it can tumor reform from granulosa cells. These tumors are most often observed in women's ovaries, although granulosa tumors have been reported in the testes. After testing, it is found that most tumors are benign. Children who have not reached puberty rarely form a benign tumor called a tumor of juvenile granulosa cells.
tumors bGranulosa carries are a smooth and rounded look. Internally, tumors contain cysts that can be filled with blood. Tumors cause estrogen level changes, detectable throughout the body. The most likely treatment is surgical removal of the tumor. After surgery, estrogen in the body returns to normal levels. The cause of these tumors is unknown.