What factors affect erythropoetin levels?
erythropoetin (EPO) is the main hormone or catalytic chemical that regulates the continuous production of red blood cells, oxygen carriers to all tissues of the human body. Sometimes it is also called hematopoetin, for a prefix that means "blood". In addition to stimulating EPO production, it also extends the natural life of existing red blood cells. The two most important natural metabolic factors affecting erythropoetin levels are corresponding to red blood cell or oxygen levels in the bloodstream. However, EPO can be synthesized and extracted in the laboratory, allowing people in need or wanting to increase blood levels.
The production of red blood cells is a complex process called erythropoiesis. In the developing fetus lies responsibility on the liver organ. When his skeleton was sufficiently formed, his bone marrow takes responsibility, while the liver accepts a new responsibility for the destruction of spent blood cells.Epo is a critical reagent in the earliest stages of red blood cell development in the marrow. EPO is glycoProtein, protein bound to two or more simple sugars. When blood sugar fluctuates, the levels of erythropoetin may fluctuate appropriately.
It is possible that the levels of erythropoetine will increase, because the need for the human body either grows red blood cells or oxygen, considering the main lever determining its normal blood concentration. Hypoxia, low oxygen in the blood, which is a normal situation during an extended, intensive aerobic activity, triggers the kidneys to produce EPOs. Chronic kidney and othernemics that cause anemia, the insufficiency of red blood cells, seriously affects the levels of erythropoetin. Other medical situations such as radiation exposure from cancer therapies may have the same effect.
hormone is also critically necessary in steps that lead to the ability of blood to precipitate and seal wounds, internal and external. When any part of the human body releases chemical tThe trauma signal into the bloodstream, one of the answers is to increase the level of erythropoetin. The injuries caused by the nerves will also start it. After losing blood from hospital operations and corresponding decrease in erythropoetin levels, some studies of EPO -based drugs recommend, while other studies discourage this because of its role in promoting blood to form clots.
Synthetic EPO produced in laboratories is classified as a drug increasing performance. Of course, their use increases the levels of erythropoetin, which increases Red Blood cells that give more oxygen to muscle tissues that give them greater strength and stamina. However, blood and urine tests can potentially detect minor differences from natural EPOs and professional athletes are commonly tested to check the so -called "blood doping".