What factors affect glucose homeostasis?
Diet, disease processes and medicines are some of the factors that affect glucose homeostasis. Human homeostasis is an internal balance or equilibrium system that monitors and regulates the complex function of the body and ensures that normal condition is maintained. The average glucose levels range from approximately 65 to 110 milligrams per deciliter (mg/dl) of blood. When the levels fall below 65 mg/dl, causing hypoglycemia, the pancreas pancreas excludes hormonal glucagon, which triggers the transformation of glycogen stored in the liver into glucose. When levels exceed 110 mg/dl, hyperglycemia is the result of a pancreas to secrete insulin, which allows glucose to enter cells and provide energy. Excessive fat income emphasizes the pancreas and causes reduced insulin stimulation. Excessive and complained alcohol consumption causes liver damage, which disrupts the transformation of glycogen. Sophisticated sugars and simple carbohydrates lead to obesity, which also leads to a reduction in insulin secretion and the condition knownLike Prediabetes.
injuries and disease affect glucose homeostasis because the body increases blood sugar levels in an effort to provide energy necessary for tissue repair. Adrenal glands secrete hormones of adrenaline and cortisol, which stimulate glucose production during physical activity or stress. The small intestine is excreted by the hormone known as incetin, which stimulates the pancreas to secrete insulin. Disorders affecting adrenal glands or small intestine disrupt the production and use of glucose. Hypothyroidism inhibits the release of glucose from the liver, while hyperthyroidism increases.
Whether acquired or genetic, diabetes mellitus is the most common cause of glucose homeostasis. When Langerhans islands in the pancreas disorder, the organ cannot exclude glucagon or insulin as needed. When insulin secretion decreases or terminates, individuals must use oral antidiabetic drugs or take insulin injections. Studies show that the normal aging process reduces these beta cells on average at a speed of one percent with each year that passes. This rate increases to 1.5% in individuals with diabetes.
Many different prescription drugs affect hormones and authorities responsible for regulating homeostasis of glucose. Doctors often prescribe diuretic drugs that reduce the body of excess fluid and lower blood pressure. These drugs also affect potassium levels that indirectly affect glucose levels. When potassium levels increase in the blood, glucose levels decrease and vice versa. Beta blocking antihypertensive drugs reduces blood pressure, but also inhibits insulin secretion.
If the patient does not have diabetes, doctors prefer antihypertensive effects of drugs over the possibility of changing homeostasis of glucose. Health care providers may also require some patients to use niacin supplements that increase high density lipids and reduce triglycerides. Niacin also inhibits insulin secretion. Patients whoThey use antipsychotic drugs that include clozapine, olanzepin and risperidone, can experience a condition known as insulin resistance. Although the abdominal effect excludes insulin normally, the body does not respond to it and maintains glucose trapped in the blood.