What is an endothelial nitric oxide oxide?
nitric oxide (NO), soluble gas, is a physiological signaling molecule found in humans and many other vertebrate animals. Endothelial nitric oxide is produced in the lining of blood vessels, where it affects blood pressure causing vasodilation, which is the spread of blood vessels. It also affects arterial growth and immune responses. Reduced production or availability of nitric endothelial oxide characterizes diseases such as atherosclerosis, where it contributes to high blood pressure, inflammation and sometimes blood clotting.
The whole circulatory system, including the arteries, is lined with an endothelium that controls blood pressure and serves as a selectively permeable barrier between the interior of the blood vessels and the external environment. Nerves regulating endothelium release acetylcholine neurotransmitter. This sends a signal to endothelial cells so that it is not. Nitric oxide triggers vasodilatation, releases the arterial wall and causes blod pressure in the container to decline.
The central feature of endothelial dysfunction is to fully dilateate blood vessels failure. WhenThe production or release of endothelial nitric oxide is impaired, followed by vasoconstriction, as the blood vessel narrows. This in turn causes an increase in blood pressure. Without the control effects of nitric oxide, immune cells such as leukocytes are proliferated, causing chronic inflammation. Plates that regulate blood coagulation also proliferate, begin to follow the endothelium and create a blood clot that prevents circulation.
physiologically there are many signals that cause the production of endothelial nitric oxide in healthy cells. The level of blood passing through the arteries and veins is considered the most important. Complications of obesity, hypertension, high cholesterol levels, genetic disease and lack of exercises contribute to endothelialmudysfunction and reduce nitric oxide production. Exercise and reduced intake of saturated fats increase NO. Amino acid arginine is a precursor molecule from which nEvyba no, so consumption of foods that are rich in arginine, such as beans and cold waters, can help increase production without.
fats are prevented from sticking to the arterial wall with nitric oxide. With high levels of low density in the bloodstream, cholesterol is transmitted to the arterial walls. Nitric oxide levels allow cholesterol to be maintained. Cholesterol observance of blood vessel walls is part of a chain reaction that causes damage to the endothelium, leading to the formation of fibrous plaques that lead to atherosclerosis. It also causes decreased production of endothelial nitric oxide oxide.
nitric oxide, in the form of nitroglycerin, is used to treat angina. Nitroglycerin ingestion to treat heart pain is converted to NO. It expands the Veins, reducing heart load by reducing the amount of blood returned to the heart in every heart cycle. The heart then has less blood to draw.
other drugs indirectly stimulate the production and use of nitric oxideo. Penis erection is caused by signals from nitric oxide to dilat local blood vessels. Some drugs of erectile dysfunction may increase nitric oxide signaling to penile blood vessels so that they work in a healthy and normal volume.