What is the epidermal growth factor?
epidermal growth factor (EGF) is a protein that binds to cells in the body to regulate their growth. Typically made of 53 amino acids and three disulphide bridges, can often be seen in abundance in human saliva, blood plasma, plasma and white blood cells. Polypeptide protein usually helps to maintain tissues in the mouth, esophagus and digestive system, as well as secretion of mucous membranes from acids, chemicals and bile. It is one of several proteins that can bind to associated receptors on cells to regulate normal activity. When the epidermal growth factor is bound to the cell, the chain reaction usually leads to deoxyribonucleic acid synthesis; Protein disorder may disrupt normal cell division control.
In addition to dividing one cell, the epidermal growth factor can cause reactions that also communicate with signals and others. Usually, it first stimulates proteins in the receptor location and then the signals are common in a cascade effect. Biochemical changes in the cell may arise and hungerNY calcium, glycogen and other levels of proteins often grow. This process is often changed by the expression of the gene and the creation of a new DNA can be triggered before division. The epidermal growth factor is bound to the receptor, which usually has a part protruding from the cell membrane, and the part inside that transmits signals to other areas inside.
When an epidermal growth factor molecule is associated with a receptor, it can form a binding domain. The components of this small scale include molecules that grab the EGF anti -Anen. Two rod -shaped structures can react from amino acids and one often relaxes to allow the receptor to chemically interact with the others. Growth factor is generally important for embryogenesis, during which it can regulate cell differentiation into specific tissues.
Sometimes Epidermal Growth Factor does not work properly and if the signaling process becomes excessively active, they may occur uRaty types of cancer. The result may be too much EGF to create or mutant forms of the receptor. Medical research has often focused on collecting genetic and structural data related to epidermal growth factor. It is assumed that drugs that can inhibit a protein receptor reduce the risk of cancer. They sometimes work by blocking the molecule from the binding or preventing messages from being sent when the molecule binds to the receptor.