What is mesangium?
mesangium is a layer of tissue inside the kidney. It surrounds and supports the node of extremely small blood vessels called glomeruli. There are many glomeruli inside the kidneys and filter blood as part of the urine production process. Mesangium plays a role in this filtering process and also helps to remove undesirable particles from this kidney area. Mesangium changes affect kidney anatomy and are involved in the development of certain kidney diseases. On the outside of the blood vessels lies the type of thin shell or membrane and the cells of mesangia lie between this and endothelial cells. In parts of the glomerulus, where two blood vessels lie very close together, they can share the same membrane. Mesangial cells are often found at these points.
When the blood is filtered through the glomeruli, it passes from the blood vessels through the holes in the walls, through the membrane, and then through the gaps in a narrowly knitted layer of cells called podocytes. The speed at which the filtering occurs is affected by the available surface, and Mesangium can change it. Mesangial cells are a schdOpny to download like muscles. This can cause the blood vessels to break and grip and divert blood flow away from some areas of the glomerulus, reducing the area available for filtration. Cell relaxation has the opposite effect, increases the surface area and the speed of filtration.
In some cases, the mesangial cell is able to act as some white blood cells in the immune system when it consumes foreign particles connected to antibodies. Mesangium cells can also eliminate substances involved in inflammation. This can be an important part of the body's response when part of the kidney is injured.
Sometimes illumination of kidneys imes can cause mesangium to spread, with mesangial cells divided and increasing the number. This can be seen in conjunction with diabetes or in a disease known as glomerulonephritis. Mesangium enlarged and an abnormally high number of intermediate cells can interfere with kidney function, which eventually leads to kidney failure. Diabetic kidney disease is treated with a combination of drugs and changes in lifeThe style, while the treatment of glomerulonephritis depends on the basic cause. Blood pressure reduction is an important part of treatment in both cases and dialysis or kidney transplantation can be considered as the last option.