What Is the Average Life of a Red Blood Cell?

Radioactive iron is used to measure the life span of red blood cells. The life span of normal human red blood cells is 100-130 days, with an average of about 125 days. 51Cr labeled erythrocyte method: half-life: 26.57 ± 3.11 days, average life span: 46-90 days.

The life span of red blood cells is 100-130 days, with an average of about 125 days. In addition, the use of 51 chromium-labeled red blood cells reduces 50% in circulating blood, that is, the T50 half-life is used as a clinical indicator. This method is relatively simple, 25-40 days for normal people, and less than 20 days In order to shorten the time, the life span of patients with hemolytic anemia is significantly shortened below 17 days. For example, sickle cell anemia is shortened to 5-15 days, and paroxysmal nocturnal hemoglobinuria (PNH) is shortened to about 10 days.

Name: Red blood cell life

category: blood

Normal red blood cell life

Clinical significance of red blood cell life

Abnormal results: Reduced: all types of hemolytic anemia. People to be checked: anemia, hemolysis, proteinuria.

Red blood cell life considerations

Not suitable for people: blood transfusion three weeks before and during the test. Before inspection: Stop taking vitamin C for one week, because it can reduce the hexavalent 51Cr to trivalent and reduce the labeling rate. After the test: It can help to determine whether there is a related disease based on the life of different red blood cells.

Red blood cell life check process

Use radionuclides to mark red blood cells in vivo or in vitro, and observe the rate of disappearance of radioactivity in these labeled red blood cells, so as to obtain the daily death percentage of red blood cells or the checkpoint of red blood cell renewal. The time required for 100% renewal is the life of red blood cells. In addition, radionuclides can also be used to participate in erythrocyte production, and the time of disappearance of radioactivity in red blood cells can be measured to obtain the life span of red blood cells.

Red blood cell life- related diseases

Eperythrozoonosis, anemia caused by excessive hemolysis, congenital erythrocyte membrane disease, bone marrow anaemia, simple red cell aplastic anemia, pure red blood cell aplastic anemia in children, neonatal erythrocytosis-high viscosity syndrome, Pregnancy with erythrocytosis, pregnancy with megaloblastic anemia, erythrocytosis fundus

Red blood cell life- related symptoms

Red blood cell life shortens, hematocrit is high, red blood cells are low, red blood cell distribution width is high, red blood cell distribution width is low, red blood cell volume increases, red blood cells increase-high viscosity, red blood cells are string-like, erythrocyte syndrome, Erythrocytosis ^[1]