What Is the Corneal Endothelium?

Artificial corneal endothelium. Tissue engineered human corneal endothelium (artificial corneal endothelium) developed by the Corneal Tissue Engineering Laboratory of Ocean University of China after 9 years has successfully completed corneal transplantation experiments in rabbits, cats and monkeys. The laboratory It is expected that a complete artificial cornea will be developed within 3 to 5 years.

Artificial corneal endothelium

Right!

Artificial corneal endothelium. Tissue engineered human corneal endothelium (artificial corneal endothelium) developed by the Corneal Tissue Engineering Laboratory of Ocean University of China after 9 years has successfully completed corneal transplantation experiments in rabbits, cats and monkeys. It is expected that a complete artificial cornea will be developed within 3 to 5 years.

1.The cornea is a layer located on the anterior wall of the eyeball

A black and white domestic cat in an animal laboratory at Ocean University of China

How to obtain a large number of corneal seed cells with normal structure and function in vitro and how to develop and screen biocompatible carrier scaffold materials has always been a difficult point in artificial corneal research. After scientific research, researchers from Ocean University of China have finally used the modified epithelial layer to modify the amniotic membrane as a scaffold, and cultured the corneal seed cells under the appropriate temperature and culture conditions, and succeeded in animal experiments. Seen on the certificate of results of the National Science and Technology Commission, experts organized by the Ministry of Education believe that this technology has established the first non-transfected, non-tumorigenic human corneal endothelial cell line in the world. Research and early application into clinical applications.

At present, the Key Laboratory of Corneal Tissue Engineering of Ocean University of China has cooperated with Qingdao Yuming Biotechnology Co., Ltd. to complete the construction of a third-class medical device production workshop, and has obtained a third-class implant material and artificial organ production license. The industrial production of tissue engineered human corneal endothelium is ready. This laboratory also cooperated with Qingdao Zhonghao Bioengineering Co., Ltd., and began to focus on the research of the manufacture of complete artificial cornea. It has successfully reconstructed artificial corneal epithelium, and plans to create a complete artificial cornea and complete animal transplantation experiments within three to five years.