What is the function of receptors dopamine?
Dopamine receptors can be classified into five subcategories, receptors D1, D2, D3, D4 and D5. Each of these types of receptors serves different functions depending on the area of the body where they are located. Motor activity, memory and learning are all functions of these receptors. Dysfunctional receptors of dopamine can cause many different diseases and disorders such as addiction, schizophrenia and Parkinson's disease. The Forward Locomotion is controlled by activation of D1, D2 and D3 receptors in the ventral brain stretch area where the limbic system is located. Activation of different types of D2 receptors, such as author or postsynaptic receptors, has a direct impact on increasing or reducing forward locomotions. D3 receptors work similarly to D2 receptors because they can either evoke or inhibit motor activity. D1 receptors do not have impactmot activity in themselves, but it is necessary for maximum movement when paired with D2 receptors.
reward and strengthening also represent the primary function of dopamine receptors. The best -known example is given in cases of drug addiction and abuse. When certain psychostimulatory drugs such as cocaine are accepted, D1 and D2 receptors are activated, creating an euphoric feeling associated with the drug. Dopamine is released when medicines are taken and the amount of dopamine produced reduced during withdrawal. During the withdrawals D2 receptors cause a person looking for more cocaine or other stimulators, while D1 receptors try to reduce the drive and look for a medicine.
Despite certain inconsistencies in data, there is a general consensus that dopamine receptors have a function in learning and memory. The D1 and D2 receptors are activated in Thippocampus, the brain area responsible for memory, and it has been shown to improve retention in rats. In the monkeys, the studies show that activation of D1 and D2 in the prefrontal cortex, which is an area of brain that controls behavior and expression, improves memory. It is assumed that the recipeOry D5 is the force for the effects of D1 receptors in the hippocamp. D3 and D4 receptors remain a bit of a mystery for scientists, but it is believed to support D2 receptors in hippocamp and prefrontal cortex.
dysfunction of dopamine receptors is responsible for various diseases and disorders. Social phobia, disorder of hyperactivity with lack of attention and schizophrenia are some examples of mental health disorders that may develop from dysfunction or excessive stimulation of dopamine receptors. Parkinson's disease, neuroleptic malignant syndrome and genetic hypertension can also develop from non -functional receptors.