What Is a Human Antibody?

Human antibody mainly refers to a mouse monoclonal antibody modified by gene cloning and DNA recombination technology. The re-expressed antibody has most of its amino acid sequence replaced by human sequence, which basically retains the affinity and specificity of the parent mouse monoclonal antibody and reduces the affinity. Its heterogeneity is beneficial to the human body. Human antibody refers to the constant region of the antibody (ie, CH and CL regions) or all of the antibody is encoded by the human antibody gene. Human-derived antibodies can greatly reduce the immune side effects of heterologous antibodies on the human body. ^[1]