What Is the Dose-Response?

The degree of biohazard to the dye depends on the relationship between the toxicity of the pollutant and the dose into the body.

Dose response

The degree of harm of environmental pollutants to the human body mainly depends on the amount of pollutants entering the human body. The body's toxic response is closely related to the toxicity of environmental pollutants. Effects and responses are often used interchangeably to describe the response of an individual or group to a certain dose of a toxic substance. Some modern toxicologists have suggested that:

The dose-response curve of S is S-shaped. When the dose starts to increase, the response changes are not obvious. As the dose continues to increase, the response tends to be obvious. After a certain degree, the response changes are not obvious. If the response rate is converted into probability units and the dose is converted into logarithmic value, the dose-response relationship curve becomes a straight line. In addition, a few dose-response relationships appear as straight or parabolic. Pollutants with a clear dose-response relationship make it easy to quantify their toxicity. Some effects are only manifested in susceptible populations; some effects often exceed the normal values of medical examinations, but the body has the ability to compensate; serious effects can cause pathological changes. Any effect that exceeds the normal physiological range shows damaging effects on the body. Some effects can only be expressed by occurrence or non-occurrence, such as the occurrence or non-occurrence of death and tumor. The minimum dose that causes adverse or harmful biological changes to the body is called the threshold dose. Below the threshold dose, the maximum dose at which no adverse effect on the body is observed is called the no-effect dose. Threshold dose or no-effect dose is the main basis for formulating sanitary standards and environmental quality standards.