What is the pathology?

Pyrogen is a protein that can cause a fever in the patient by triggering a number of immune reactions. Some are endogenous, develop in the body and others are exogenous and can be introduced through contaminated food or medicines. The exposure to the pyrogens can cause severe fever and may endanger the patient if the temperature is permanently high or accompanied by complications such as bleeding. To produce products without such compounds and testing of finished products that could pose a health risk, a number of steps should be taken. This leads to the immune system to the reaction and causes a temperature tip. If the fever gets high enough, the patient could develop a changed level of consciousness and could fall into a coma. Heavy fever can cause permanent neurological damage along with other health problems and in some cases may be fatal. If the patient was already patient, the exposure of pyrogens may reduce the patient's prognosis or long -term outlook.

one of the potential wallsRojs of these compounds are contaminated drugs. Numerous bacteria produce pyrogens, usually as part of cell walls. If they get into doses of drugs, they may cause disease in patients. Especially when the drug is injected directly, the patient's body may be affected by the pyrogen explosion and the patient could experience a serious injection reaction, sometimes in minutes.

Even sterile solutions can be contaminated unless they are driving properly during production. At every step, strict filtration is necessary to keep the content clean and be treated with caution until they are closed in the shipping package. Drug companies use periodic testing of pyrogens to control the safety of their products. If the dose contains pyrogens, the company can destroy it, depending on whether the drugs have reached the market.

Direct infections can also cause the pyrogens to release in the body. SomeBacterial infections are associated with fever and other extreme reactions caused by bacterial toxins. Bacteria can produce toxins as a by -product of other activities or when they die. Paradoxically, antibiotic therapy may sometimes be a temporary patient killing of bacteria and starting the mass release of toxins. If the infection involves bacteria known to be cautious, the doctor may be careful when prescribing, to reduce the risks to the patient.