What are Ligand tests?

tests are a method used in medicine to determine the presence and amount of molecule in a biological substance. There are different types of tests and are marked with their name. Specifically, ligand tests refer to a group of tests that measure the product from the chemical interaction between the measured molecule and the reactive substance or the receptor located on the test itself.

In the human body, the ligand molecule triggering a signal that fits into specific receptor sites located on the cell walls. When Ligand fits into its specific receptor site, it causes a change in the physical shape of the receptor, which then triggers the biological signal. This cell response is measured in the ligand tests.

Ligand tests can be used to measure a wide range of substances in the human body such as cells, medicines and hormones. Several types of biological ligand tests have been created because the human body is very complex. The measurement mechanism is made to classify tests into three main classes, including competing, uncompetitiveand miniaturized microchip tests.

In a competitive test, as a radioactive marked compound of a similar structure to the molecule examined, and instead of the binding receptor are provided on the test. When a human sample is to be measured on the test, it must compete with a radioactive molecular molecular already on the test to tie it to the receptors. The quantity in which radioactive molecules turn off the sample receptor binding can provide doctors with information about the presence and amount of molecules in the sample. Competitive tests were first used in the mid -1950s to measure hormone concentrations in humans, mainly the function of the thyroid hormone and the hormone of breast cancer.

and Secod Ligand Test Type is an uncommon test. It works in a way that is similar to the way of a competitive test, except that radioactive marked molecules on the test are available in excess, andTherefore, the sample molecules are already competing. The rate that the sample molecules are able to tie to the test receptors can estimate the amount of molecule present in the human sample. This test technology has become highly used in the mid -80s.

Competitive and uncommon essays of ligand allow one molecule to be examined at a time. The third class of tests allows simultaneous measurement of multiple molecules from a small biological sample. This is done using a miniaturized chip loaded with multiple small areas of specific receptors. They are called miniaturized microchips or micropots. This third class of test types lends the ability to measure multiple biological complexes from small samples and has toe more are used.