What Is Corynebacterium Diphtheriae?

Corynebacterium diphtheriae is a pathogen that causes diphtheria in children and belongs to the genus Corynebacterium. There are many types of coryneform bacteria, including diphtheria and diphtheria. Diphtheria-like bacteria are non-pathogenic bacteria, and common examples include pseudodiphtheria, dry conjunctiva, ulcers, and acnes. This chapter introduces diphtheria.

Diphtheria

Clinically suspected

Diphtheria is present in the patient or

by

Vaccination is effective and can significantly reduce morbidity and mortality. Children from 6 months to 3 years of age should be vaccinated against diphtheria toxoid, diabetic triple vaccine preparation or alum lake diphtheria toxoid. Vaccination is also required for persons over 8 years of age who are positive for the Sikh test. For susceptible children who have been in close contact with diphtheria patients, 1000 to 2000 units of diphtheria antitoxin can be injected intramuscularly for emergency prevention, and diphtheria toxoid can be injected at the same time to extend immunity.

Diphtheria antitoxin is a special treatment preparation. It should be injected with a sufficient amount of diphtheria antitoxin in the early stage of onset. The general dosage is 20,000 to 100,000 units. It is injected intramuscularly. In severe cases, it can be injected intravenously. Perform skin tests before using antitoxin serum to prevent allergic serum allergic reactions. The antitoxin should be given at the same time as antibacterial treatment, such as intramuscular injection of procaine penicillin, until the symptoms disappear and the culture of diphtheria is negative.