What is the human leukocyte antigen?

Human leukocyte antigens (HLA) relate to a number of genes that regulate the immune system. Proteins coded in gene cells are known as antigens that play a decisive role in organs and donors' compatibility. Antigens act as a defense against the disease and can affect autoimmune diseases. The HLA system can also determine a special fragrance of the person and influence the selection of a partner for reproduction.

This system represents the main histocompatible complex in human beings, which means they have the same or most of the same sets of genes. The genes found on Chromosome 6 form a system of human leukocyte, which encodes cell molecules that provide immune benefits of T-cells in the body. Finding two unrelated people with the same HLA molecules at this point is very rare. They found that immunbiel blood cells E System create antibodies to combat the exposure of infection. When foreign antigen is introduced through organs transplants, the immune system of the body attacks the donor tThe peak, unless compatible with the genes of the donor and the recipient of the organ or tissue. Surgeons perform antigen testing with human leukocyte to find out similar HLAs to reduce the chance of rejecting the organ.

Testing the antigen of human leukocytes corresponds to samples of potential donors with antigens found by the recipient. This evaluation together with blood types is performed for transplants including kidney, bone marrow and liver. The higher the number of identical HLA antigens in both people, the greater the chance that transplantation will be successful.

Antigen testing is also performed during paternity tests. HLA antigens named father, mother and child are compared for similarities after obtaining a sample of blood from all three. If the child produces antigens that are not present in adults, the assumed father may be excluded as a parent.

HLA types are inherited in six places on chromosome 6, some of whichThey are associated with autoimmune disorders and other conditions. A person who inherits specific antigens from their parents is more susceptible to the development of diseases, including diabetes and lupus. Cancer and inheritance diseases are also connected through antigen systems of human leukocytes, which means that doctors can now target abnormal cells before developing into cancer.