What is the role of neurotransmitters in schizophrenia?
Brain and nervous system abnormalities play a role in many health conditions, especially in mental health conditions. In the case of psychiatric disorders of schizophrenia, deficiencies and excesses in some neurotransmitters - namely dopamine, serotonin and glutamate - that transmission information in the brain can help facilitate the development of the condition. Due to the complexity of this disorder, the involvement of neurotransmitters in schizophrenia is probably part of a larger mental illness foundation, which also includes brain abnormalities, genetic predisposition and environmental stressors.
neurons are neurons of brain cells, movement and any further brain command give the brain. In order to perform their tasks, neurons must communicate. This task performs through neurotransmitters. Some neurons release these chemical messengers and neurotransmitters then attach and affect the activity of another neuronus. When this process works properly, neurotransmitters act as a type of pigeon carrier between cells, often atThe delivery of the message often returns to the original cells.
mental disorders as a whole are often misunderstood, but schizophrenia, although one of the more known disorders, is also ironically one of the most misunderstood. There are many varieties and symptoms of schizophrenia, but perhaps the most general definition of disorder is disorganization of thinking and behavior. Some individuals can see or hear things that are not present, and others can hold deceptive false beliefs about themselves or the world as a whole. Forms of schizophrenia can further affect emotional expression, speech and even prevent normal movement.
The neurotransmitter dopamine is strongly involved in the intellectual processes of the individual and its movement. Therefore, many researchers assume that this neurotransmitter could potentially be the main factor of schizophrenia. More specifically, elevated dopamine levels in the brain could be the basis of many symptoms of schizophrenia.
scientificThe evidence was supported by the role of neurotransmitters dopamine in schizophrenia. First, brain scanning of schizophrenics often show significantly increased activity in dopamine areas. In addition, drugs and conditions that increase dopamine levels often cause symptoms that are very similar to the schizophrenia indicators. For example, excessive use of amphetamine drugs can also cause paranoia and hallucinations. These drugs only indicate the brain that it has excessive amounts of dopamine, indicating the power of these specific neurotransmitters in schizophrenia.
Further strong evidence for defective neurotransmitters in connection of schizophrenia lies in common protocols with the treatment of schizophrenia. One of the most commonly used and successful drugs for the treatment of schizophrenia is clorpromazine. The main function of the drug is inhibition of receptors dopamine in the brain.
The potential causes of this abnormality of the neurotransmitter are largely theoretical. One proposed theory is a simple overproduction of dopamine. Others believe that dopamine productionIt is normal, but the substance cannot be properly divided. Schizophrenic individuals have indicated that disabled have more dopamine receptors than average, and these receptors may be more sensitive to neurotransmitter compared to other individuals.
Some theories of development of schizophrenia suggest a link between serotonin neurotransmitter and schizophrenia. Like dopamine, serotonin can affect cognitive functioning, among other behavioral reactions related to mood and impulses control. These reactions are often unusual for schizophrenics, suggesting that there is a contributing connection of serotonin neurotransmitters in the development of schizophrenia. One theory speculates that high combined levels of serotonin and dopamine create so -called positive symptoms of schizophrenia such as hearing hallucinations, while the low level of these neurotransmitters can lead to negative symptoms such as emotional reactions. Treatment of treatment of schizophrenia from clozapine to the effect of risperidone exercise on serotonin receptors Idopamine.
While the excess of the neurotransmitter is one of the possible explanations of schizophrenia development, the lack of neurotransmitter can also cause schizophrenia -related problems. Specifically, scientists have explored the potential connection between schizophrenia and the depleted level of the neurotransmitter glutamate. This neurotransmitter serves as a basis for learning and memory, so it may be surprising that glutamate suppression can cause disruption of normal thought processes. Some research even suggests that excessive dopamine receptors can lead at least glutamate receptors that only support the harmful cycle of schizophrenic mental diseases.