Is there a connection between methotrexate and weight gain?

Methotrexate is a prescription drug that slows the growth of specific cells, including skin cells, cancer and bone marrow. While some patients lose weight to methotrexate, others notice the connection between methotrexate and weight gain. The effect of weight gain was most often recorded in women using cyclophomide, methotrexate and 5-fluorouracil (CMF) for breast cancer. Since 2011, the exact cause of this side effect has not been known.

The common side effects of methotrexate include nausea, vomiting, dizziness, headaches, mouth ulcers, fatigue and blurred vision. These side effects often have a negative effect on appetite, which sometimes leads to weight loss. Patients may also notice fluid retention due to further kidney stress, which may be perceived as weight gain. Other times, patients regularly enjoy a high dose of methotrexate, notice the connection between methotrexate and weight gain.

Research with convincingly showed a connection between MethhotreXat and weight gain. Since methotrexate has been studied in combination with other medicines, it is not clear whether there is one medicine or a combination. Nevertheless, CMF therapy is known to increase lean muscle mass and fat tissue in patients. Experts have not found the cause of this increase, although it is clear that no weight gain is caused by a reduced metabolic function.

those who use methotrexate can also experience swelling or fluid retention while they are on medicines. This may be due to dehydration, interaction with methotrexate or kidney damage. Patients suffering from kidney disease should discuss this before receiving methotrexate with their doctor. Mixing additional medicines with methotrexate may also increase the risk of kidney damage to the patient. All patients are asked to discuss all the drugs they use with their doctor and Mpomlčka; Even over -the -counter medicines.

While fluid retention is not a permanent increase in weight, it temporarily increases the weight of a person. Some patients could confuse this weight gain to increase fat or muscle mass. Because this could be a sign of kidney -related swelling, any sudden addition or swelling should be discussed immediately.

Some patients also experience weight gain due to a reduced level of activity. Patients suffering from these conditions could not exercise as often as they once did. This could cause it to look like there is a connection between methotrexate and weight gain, while inactivity or a bad diet is a real culprit.