What are therapeutic antibodies?
Therapeutic antibodies are substances created by humans that are able to bind to specific proteins on the surface of cells. Such substances are generally used to treat cancer or autoimmune diseases, although precise treatment methods differ significantly. In some cases, the binding specificity of therapeutic antibodies is used to accurately supply drugs or enzymes activating the drug into precise cell locations. In other cases, proteins are used to inhabit binding areas on a given cell, reducing the effects of excessively active immune responses that characterize autoimmune diseases. Many different useful therapeutic antibodies have been synthesized, resulting in a large market for such substances.
Most therapeutic antibodies are monoclonal antibodies, which means that these are antibodies produced by the clones of one immune cell. Each monoclonal antibody is able to bind only to a single antigen. Both of these features are very important, toWhen such antibodies are used therapeutic purposes. The heterogeneous mixture of antibodies, which binds to non -specific diversity of antigens, has low therapeutic value because specific binding and accurate drug supply are two features that increase therapeutic antibodies. Monoclonal antibodies can be made to specifically focus on almost any substance; This ability is very useful for detection and for targeted drug supply.
There are many different types of therapeutic antibodies that can be produced in many different ways. Most antibodies are produced inside the mice and injected into humans to fight diseases. However, rejection is the main problem of the production of antibodies, because the human immune system attacks inhumane antibodies. The human immune system actually produces human anti-two antibodies, or Hamas to face the perceived threat representedby mice antibodies. To deal with this problem, scientists use chimeric antibodies that are a combination of human and mice antibodies or fully human antibodies that are produced in the human body to avoid immune response problems.
Many different treatment procedures used for cancer and autoimmune disease use therapeutic antibodies due to their high level of binding specificity. Some are used to activate medicines at precise cellular areas. Antibodies associated with enzymes bind to specific places on the cell; The drug is not activated until the contact with the enzyme is. In other cases, therapeutic antibodies are used to inhabit specific binding areas, so other molecules that could worsen the autoimmune disorder cannot be tied to these specific locations. This method is commonly used to combat autoimmune disorders.