What is a selective estrogen receptor modulator?

The selective estrogen receptor modulator, also known as SERM, is a compound that affects hormonal receptors activated by 17-ortradiol, more often referred to as estrogen. The selective estrogen receptor modulators are active in many different tissues throughout the body, allowing them to alleviate estrogen effects on a large scale. In some cases, a selective estrogen receptor modulator can act as an agonist, a compound that provokes some biological response by linking the receptor. In other cases, a selective estrogen receptor modulator acts as an antagonist, a molecule that suppresses the response by binding to the receptor. The selective estrogen receptor molecules may act as agonists or antagonists depending on the specific type of tissue in which they are found.

estrogens are very important compounds that act mainly as female sex hormones. Work in different roles, from maintaining mental health to balance inODY, sodium and other substances in the body. Although it is necessary to maintain health, estrogen imbalance can also lead to health problems such as breast cancer and osteoporosis. Many forms of breast cancer relies on the growth of constant supply of estrogen and spread, and osteoporosis is generally caused by a lack of estrogen. It is not unusual to treat both conditions using a selective estrogen receptor modulator.

For example, tamoxifen is a selective modrogen receptor modulator that acts as an antagonist of estrogen receptors in breast tissue. Tamoxifen treatment can therefore significantly slow down the progression of estrogen receptor forms of breast cancer, which grow rapidly with the supply of estrogen. He does so by blocking the receptor sites in the breast tissue that would normally be activated by estrogen. Tamoxifen also has a more beneficial effect: it acts as an agonist in bone tissue. Can be used to fight againstOsteoporosis, because its agonistic properties promote an increase in bone density.

by selective estrogen receptor modulator in treatment can lead to some negative effects, as they can act as agonists or as antagonists in different parts of the body. While a certain selective estrogen receptor modulator can prevent one type of cancer, it can support another. They may also have a destabilizing effect on human mental health because they affect the amount of estrogen present throughout the body and estrogen is very important in maintaining mental health.