What is Agomelatin?

Agomelatin is an antidepressant drug approved for the first time in Europe. It activates melatonin receptors in the brain to help patients with severe depression achieve a more balanced mood. The mechanism of action differs from many other drugs used to control depression, which often work on serotonin receptors. Patients on agomelatin may have fewer side effects, especially at the distance from drugs, and it is less likely that sleep disturbance develops.

Clinical studies on the effectiveness of agomelatine have shown mixed results. The test results in Europe were strong enough to deserve drug approval, suggesting that he overcome placebo, but other studies were less promising. One potential use of agomelatin is the treatment of patients who do not respond to the treatment of the first line with other antidepressants or cannot take these drugs due to drug interactions or other problems. For these patients, the drug could be useful to control depression no other options. This medicine seems to be the back of theThere are some liver function problems, including an increase in some liver enzymes. While the patient is taking medication, routine tests of hepatic function may be regularly performed to control complications. If the patient's liver is stressed, it may not be safe to continue agomelatin therapy.

One of the clear advantages of agomelatin is that, unlike many other antidepressants, it does not seem to cause serious withdrawal symptoms in stopping patients. People who decide to stop taking antidepressants or switching drugs can experience serious symptoms such as increased depression and confusion. These symptoms usually do not develop with the end of agomelatine, which allows patients to safely stop using Medicationt If they feel they don't work for them, want to switch drugs or want to stop antidepressant therapy.

Recommendation for treatment for severe depressionThey decide to consult and drug therapy. Patients can use a mixture of medicines and counseling sessions to solve specific problems, develop management skills and aggressive management of their condition. Some may have to continue to take antidepressants throughout their lives to reduce the risk of other depressive episodes; Others may decide to stop taking medication when they begin to feel better, but continue the therapy, so they have a problem for solving problems as soon as they are created. Therapy is highly individualized and patients can consider it useful to meet several providers to identify a good match.