What is Apixaban?

Apixaban is an anticoagulant used to prevent blood clots. This medicine is given to patients who have recently undergone knee or hips surgery and atrial fibrillation patients. It is not yet available to the public, although initial studies show that it is an effective treatment. There are a number of enzymes that play a role in the process of creating blood clots. Apixaban interferes with XA factor, while other anticoagulants prevent blood clots to interfere with other enzymes. Recent drug studies have shown that apixaban is equally or more effective than competing drugs. When it was tested in 2007 against competing drugs, it turned out to be equally effective in preventing blood clots after knee surgery. Other 2010 studies have shown that it is more effective than its competitors to prevent dangerous blood clots that can form as a result of hip surgery.

The main danger of accepting anticoagulance such as apixaban is that the patient may experience a life -threatening bleed. With the ability to create blood clots disturbed, bleeding continues uncontrolled, which can lead to serious blood loss. This is a risk associated with the use of anticoagulance, and in most patients it has not been shown that apixaban causes more or less risk of bleeding than any other medicine.

Although the Apixaban seemed well in the studies, it caused dangerous bleeding in patients who suffered from acute coronary syndrome and who, in addition to Apixaban, received anti -aggregation therapy. Studies were stopped for these patients in November 2010, although drugs are still considered safe for other patient groups.

While the precipitation is necessary to control bleeding, under certain circumstances this may be a prosecutive risk for the patient's life. The joint or hips surgery can put the patient at a special risk of developing clots in large blood vessels of the legs. These clotsY, if they relax, can be trapped on the way to the heart or brain, leading to a stroke or heart attack. Many patients who have undergone these types of operations receive anticoagulants such as Apixaban to help reduce the risk.