What is the influenza neuraminidase?
Influenza neuraminidase is an enzyme that plays a role in the spread of the influenza virus. The enzyme acts by breaking the ties with the host cell to allow the virus to circulate the virus through the body, rather than get stuck. This facilitates the movement of the influenza through the airways and to other areas of the patient's body to create extensive infection. One class of antivirus medicines known as neuraminidase inhibitors works in combating influenza by binding to this enzyme, so it cannot work.
flu virus is known for its mutation capacity; Every flu season is a bit different and therefore it is very difficult to fight. One of the things that changes is the structure of neuraminidase on the surface of each virus. Another complex, hemaglutinin, is also involved in the virus virulence. The influenza is classified by the type of hemaglutinin and neuraminidase on its designation surface.
Hemaglutinin on the surface of the virus helps to bind to the cell so it can infect it while influenza neuraminidase cleaves when the virus is readyto move. Together, paired complexes allow the virus to infect and spread and can also jump between patients when people cough without covering their mouths or sharing tools. The structure of influenza neuraminidase may vary and can determine what type of virus infects.
As the influenza viruses are replicated, they mutate. Changes in the structure of the influenza of neuraminidase can result in the virus of guys or in a new trunk that can jump species or become particularly aggressive. The changes that prefer the virus tend to persist because these viruses continue to replicate and spread their genetic heritage elsewhere. Scientists of the influenza study virus mutations to learn more about how they spread over time and change SEA to develop appropriate treatment.
Inhibitors of neuraminidases can be administered in the early stages of infection to reduce the time when the patient spends the patient's feeling. Medicines can also be useful for patients who mThere are problems with the fighting for the virus themselves because of the immune compromise. The physician may feel that they are indicated if the patient meets a specific profile and may prescribe oral or injection forms. Access to these drugs is usually limited to prevent excessive use, as doctors do not want to encourage the virus to develop adaptations that can be used to administer influenza inhibitors.