What is the toxicity of lidocaine?
Lidocaine toxicity is a reaction to the effects or amounts of dosing lidocaine, which is common topical anesthetics. Lidocaine reactions move from mild to severe. Slight side effects of lidocaine may include dizziness, increased heart rate and respiratory frequency, increased blood pressure, involuntary eye movement and unconsciousness. Severe reactions include drowsiness, brain seizures, reduced blood pressure and heart rate, reduced respiratory frequency and unconsciousness.
Lidocaine toxicity is a serious medical emergency because symptoms may occur without warning and stimulating complications threatening life such as brain seizures, cardiac arrest and oxygen. The toxicity of the risk of lidocaine differs somewhat among individuals. Lidocaine is metabolised by the liver and patients with impaired liver or liver disease can experience more serious complications with lower doses than health patients. Doses of 10 mcg/ml or more induce serious toxic reactions, but for some patients dosing 6mcg/ml mayto act.
Toxicity is also dependent on many other factors. Lidocaine is a synthetic amino amid an anesthetic and can cause reactions in patients with low proteins. Excessive acid in body fluids from kidney dysfunction, called acidosis, can cause lidocaine toxicity. Patients on beta-blockers or some antibiotics may experience serious interactions with drugs on lidocaine.
Generally, most cases of lidocaine toxicity occur in unintended overdose by drug. It is difficult to control the dosage of lidocaine, which is used as a spray, especially when applied to a highly vascular surface of the body, such as mucous membranes of the mouth and neck. The injection rate can also affect toxicity, because the faster the speed of injection, the less capable of the body processes the medicine.
While the toxicity of lidocaine is a serious health, serious reactions, long -term complication and the death of JSou very rare. Doctors are aware of the risk of this anesthetic and monitor its use and patient during the medical procedure. Most patients suffering from lidocaine toxicity can only experience mild dizziness or discomfort. Lidocaine reactions decrease rapidly when the body is absorbed, metabolizes and inoculates the effects of the drug.
Lidocaine use varies in medical procedures, but is commonly used as a local anesthetic for dental procedures, injected as a local anesthetic for block of dental nerve or surgery and applied to the skin as a current solution for relief from mild to mild pain. Lidocaine is unusually used as a treatment of poststerpetic neuralgia, as antiarrhythmic, as well as to alleviate jelly. When Lidocaine is used as an inhalant, it acts as a suppressing cough.