What is LofEPRAMIN?
Lofepramine is a tricyclic antidepressant (TCA), developed at the beginning of the 80s and is most famous in European countries through brands such as Tymelyt®, and Gamil® and according to the general name Lomont. The drug has never been approved or sold in the US. Like many TCA, LofEPRAMIN increases available or free number of neurotransmitters, serotonin and norepinephrine, which can alleviate depression and anxiety. Not all patients can take this medicine and have both benign and serious side effects, although some report that the drug has fewer side effects than other TCA.
This drug is indicated when depression contains symptoms of anxiety or panic, and may be prescribed to treat anxiety disorders. It appears to have a greater effect as an anxiolytic or anti -tanx agent than as an antidepressant. TCAs are less often prescribed than newer medicines such as selected serotonin reuptake inhibitors (SSRIS) or serotonin-norepinephrinhibitors reuptake (SNRI) because they have tendencI have more side effects. SNRIS can be used in particular instead of TCA because they have similar effects with lower side effects. SNRIS and TCA share other similarities, and they both seem to have a higher level causing withdrawal symptoms, which means that medicines such as lofepramine should be narrowed after interruption.
Some people should not use lofepramine. These include children, women who are pregnant or plan to conceive, people with bipolar disorder and those who recently had a heart attack or stroke. The advantages of using lofepramine must be considered if patients have conditions such as enlarged prostate, a history of heart disease, seizure disorders or glaucoma.
There are important warnings of lofepramine; In particular, it can increase suicidal thinking or behavior, especially between adolescents and young adults. And Number drugs interact with this drug that may require a dose change or which mayObit that the medicine can ineffective. These include antihistamines, hormonal contraceptives, antacides, medicines against tour, medication against garlic or blood thinner and some free -the -counter medicines for cough or cold. Patients should not accept prescription for lofepramine without first providing doctors a list of all prescribed and over -the -counter medicines and any herbal, mineral or vitamin supplements they use.
less severe side effects associated with lofepramine are nausea, headache, dizziness and drowsiness. There may also be blurred vision, constipation, sexual dysfunction, dry mouth and sweating.
People should report at once or obtain medical care if they experience more serious side effects such as allergic reaction, rash, jaundice or seizures. Other serious side effects include confusion, hallucinations or changed thinking, suicidal thinking, extreme agitation and severe restlessness. The ringing in the ears and heartbeat should also be reported immediatelyEvent, such as rhythm and palpitation interference. The drug may also affect the normal number of blood cells and may result in hypotension and doctors should explore.
Not all people experience side effects with lofepramine, or they may have temporary to be resolved with continued use. It is difficult to predict the individual's reaction to this medicine, which is variable. Many people consider this drug useful and continued to be used in many European countries.