What is the reason for using statins at night?

Doctors often recommend that patients use statins at night, as medicines can more effectively reduce cholesterol levels with low density (LDL) when they are taken in the evening. These drugs work by blocking the activity of the enzyme in the liver responsible for the production of LDL and its concentration tends to rise at night. The use of drugs with increasing the level of the enzyme may be the most effective. In some statins, the concentration of the drug remains high enough for 24 hours that the dose time is not as critical.

In early clinical trials, scientists had statins at night for existing knowledge of cholesterol production in the body. They knew that cholesterol levels tend to increase while people sleep because it is when the most active liver enzyme is involved. On the basis of this information, they decided that the statins would be most effective when they were in the evening, allowing the peak of the drug level to accumulate in a liver enzyme tandem. The drug could block enzyme, reduce the productionsKCI LDL and perhaps increase lipoprotein with high density (HDL) or "good cholesterol" simultaneously.

Using information from clinical studies, manufacturers recommended that patients take these drugs in the evening. This information was largely repeated by medical practitioners who told patients to use statins at night. Scientists have conducted several studies with different types of statins and found that overall LDL levels tend to be lower in patients who use evening dose, unlike patients who take medication in the morning. These studies have supported recommendations.

Research on specific statins has shown that because their sera levels remain stable, which means that the drug remains consistent in the body for a long time, it may be safe to take them in the track. The physician may consider these medicines if there are worries about the patient's drug schedule and the ability to maintain treatment recommendations. Patients with whom the obt isImplifiers to use statins at night, they could switch to these drugs to see if they work for them.

As with many drugs, statins should be taken according to a consistent schedule. People who take drugs at about the same time each day maintain the level of serum consistent, allowing the drug to work continuously. For those who take statins at night, it is important to choose the timing of the dose that will be easy to remember and follow.