What is involved in the production of erythropoetin?

Erythropoetin production, a hormone that regulates how many red blood cells are released, is usually done in the kidneys. A small amount is also produced in the liver. Erythropoetin production usually increases when a person loses blood or does not get oxygen. The protein scanning oxygen is present in the liver and the kidneys, and when blood levels are too low, it causes erythropoetin production. In the kidneys erythropoetin is produced by cells in small tubes where urine is formed, and in the liver synthesizes those liver cells that surround veins. This type of structure is called glycoprotein. The process of production of red blood cells, which stimulates erythropoetin, is called erythropoiesis. This means that bleeding or traveling to high altitude will increase production, while something that increases red blood cells such as blood transfusion tends to reduce erythropoetin production. Once it is an increase in red blood cell levels, the blood may carry more oxygen and it turns off the productionor erythropoetin. After the production has been turned off, if it reduces the levels of red cells, the production of erythropoetin is re -launched.

When people travel to high altitudes, less oxygen is available in the atmosphere, erythropoetin production first rises sharply. Over the next few days, the lungs will work harder and oxygen levels in the blood. This is gradually caused by erythropoetin production. Within a few days, extra blood cells have been formed in response to an initial increase in erythropoietin helping to transport more oxygen to the body tissue. As long as the person stays in a high place, the number of red articles remains higher than usual and people who are used to living in the mountains have a permanently high standard.

and also be produced in response to low oxygen levels, more erythropoetin is also created when people take cobalt salts. These are potentially toxic substances that increase the number of red CRVince, but which can also harm the main organs such as the heart and increase the risk of cancer. Increased levels of hormones that control sexual development in men can also affect erythropoetin production. These hormones, which are also found in women, have been found to increase the amount of erythropoetine formed and relaxed from the bone marrow.