What is the accessory system?

The

complement system is part of the body's immune system and consists of a series of protein molecules that activate each other in a sequence known as a cascade. The complement proteins are present in the bloodstream and in the liquid that surrounds body tissues. When a pathogen enters the body, such as harmful microorganism, the system of supplements and proteins start to activate each other along one of the three ways. These are known as the classic way of the accessory, an alternative complement path and a lectin road. The activity of the additional systems covers pathogens, so they are easier to target the body's immune cells and actively destroy those that are already connected to the antibodies.

In the immune system, the organs, tissues and cells to defend the body against harmful organisms and other substances that cause the disease work. The accessories system is part of what is called an innate immune system that is present at birth. This is different from the odadaptive immune system that comes into the game when microbes are recognized after pa diligent attack. These antigens may be proteins present on the surface of unicellular bacteria. When the antibodies connect to the antigens, it can activate the classic way of the additional system system. The lectin path and the alternative complement path are activated by different methods.

In the classic path, part of the first complement protein, known as C1, binds to an antibody associated with antigen on the surface of the bacteria. This bond activates another part of C1, which becomes an enzyme capable of divided into half of the additional proteins known as C2 and C4. The active part of the C4 then binds to the bacterial surface and the active part of C2 is connected to it. This combination of parts C2 and C4 also acts as an enzyme that breaks other complement protein, C3.

Part C3 binds to a cellular surface so it is more attractive for immune cells known as phagocytes, while some of them bind to C5, which helps othersM supplementary proteins to activate it. C5 is divided and forms what is called a membrane attack complex along with C6, 7 and 8. The membrane attack complex allows proteins C9 Complement to create a tube that creates a channel through the membrane of bacterial cells. The water is drawn into the cell and bursts and destroys the bacteria.

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