What Is the Pronephros?

The common name of NE, NE is the abbreviation of norepinephrine (INN: Norepinephrine, also known as Noradrenaline, abbreviated NE or NA). -Aminoethanol is a substance formed by the removal of N-methyl from adrenaline. It is a neurotransmitter, which is mainly synthesized and secreted by post-sympathetic neurons and adrenergic nerve endings in the brain. It is the main transmitter released by the latter and a hormone, which is synthesized and secreted by the adrenal medulla, but with less content. Norepinephrine in circulating blood comes mainly from the adrenal medulla.

NE

(Norepinephrine)

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NE common name, NE is

Its weight

Norepinephrine is rarely absorbed on mucosal surfaces, subcutaneously or intramuscularly due to intense local vasoconstriction. Oral is destroyed by alkaline intestinal fluid in the intestine, and is destroyed by combination and oxidation when passing through the intestine and liver, so it is not effective. Therefore, this medicine is mainly administered by intravenous injection. The exogenous norepinephrine that enters the body quickly disappears from the blood and is taken up by the norepinephrine nerve, which enters the heart and adrenal medulla. It is further metabolized to norepinephrine by catechol- O -methyltransferase (COMT), monoamine oxidase (MAO), and phenylethanolamine- N -methyltransferase (PNMT) in the liver and other tissues, 3,4 -Dihydroxymandelic acid, 3-methoxy-4-hydroxymandelic acid (VMA), 3-methoxy-4-hydroxyphenyl ethylene glycol (MOPEG) and epinephrine are inactivated. After 96 hours of intravenous injection or instillation of labeled norepinephrine, the percentage of NA and metabolites in urine: 4-16% of the original form, 8% of the combined NA, 32% of the VMA, and norepinephrine combined 18%.