What is the role of dopamine?

Dopamine denotes a neurotransmitter catecholaminine, especially for regulation and control of sensory and motor activity. It is produced in the brain and, as a neurotransmitter, its role is necessary to initiate or end the signals of nerve cells and allows continued communication of neurons across synaptic gaps. Although dopamine, which is made in small amounts, affects mood, as well as reproductive and pleasure seeking behavior. Too much of this causes symptoms of schizophrenia, while too little causes tremor typical of Parkinson's disease. Responsible for Dopamine production, nigra substantia is a center -inson group of neurons necessary to communicate with basal ganglia. This neurotransmitter is also produced by the hypothalamus and the ventral tegmentum, the structure of the midbrain located directly next to the nigra substantia. Mechanism of behavior in search of pleasure called a system of reward circuits includes the tegmentum and the core of Accumbens, the limbic systemic structures consisting of nerve buSome producing dopamines. Nucleus accumbens receives information interpreted as a reward, as satisfaction or as pleasant from the Tegment, and dopamine is a neurotransmitter. It plays primary role depending on the effect of dopamine is directly affected by commonly abused drugs, especially cocaine, heroin and amphetamine.

schizophrenia's etiology has been associated with excessive dopamine levels, but it is also assumed that other neurotransmitters also have a role. Schizophrenia concerns serious men's diseases characterized by sensory distortion, irrational thinking and downloading. The theory of dopamine role in schizophrenia claims that psychotic symptoms such as hallucinations are caused by abnormally high levels of dopamine, caused by hypersensitivity or excessive amounts of receptors. Drugs have been shown to be particularly effective in the treatment of schizophrenia that causes dopamine receptor blocking, therebythe amount produced is reduced.

characterized by tremor while resting, losing coordination and mixing of walking, Parkinson's disease is caused by a deficit of dopamine levels due to the destruction of nerve cell receptors located in the nigra substantia. At a time when motor manifestations occur, up to 80% of cells, which usually in people over 60 years of age, were destroyed. Treatment with oral dopamine would seem effective, but because it cannot easily penetrate the barrier of bloody razite, another medicine that can turn into the recommendations of dopaminumed to as levodopa is commonly used. With the progression of Parkinson's disease, Levodopa will become less useful.

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