What Is Comparative Genomics?

Comparative genomics is a discipline that understands gene function, expression mechanism, and species evolution by comparing known genes and genomic structures based on genomic maps and sequencing. Utilizing the sequence and structural homology between the genomes of model organisms such as mice, fruit flies, E. coli and human genomes to clone human disease genes, reveal gene functions and disease molecular mechanisms, and elucidate the evolutionary relationship of species and the internality of genome structure. (Li Shengbin) ^[1]