What are the different methods of collecting stem cells?
Stem cells transplantation, also known as bone marrow transplantation, are used to treat various diseases, including leukemia, lymphoma and multiple myeloma. The stem cell donor may be a patient, corresponding to a biological member of the family or corresponding to unrelated donors. The three primary methods for the collection of stem cells are bone marrow extraction, peripheral blood and peripheral blood and cord blood harvest. During the surgery, the donor's bone wood is extracted from several places in the hips using a special needle. Approximately 1 to 2 liters (0.94 to 1.89 liters) of bone marrow, which represents about five percent of the patient's total marrow. After bone marrow extraction, all fat or fragments of the bone are filtered and removed. The gift is then transported to the laboratory, which will be processed earlier for transplantation later or transferred immediately to the recipient.
in the last airmanH with the peripheral blood adferes has become a popular method for collecting stem cells because it does not include surgery. To prepare for afferes, the donor usually supervises a special medicine, known as a factor stimulating granulocytes (G-CSF) for several days to stimulate the pulp to release more stem cells into the bloodstream. The blood is then removed from the donor via IV located in a large vein in the arm or in the central line located in the chest, neck or arm. Blood further passes through a machine that separates stem cells from red cells, white cells and plates. Cells that are not needed will then return to the donor another vein in the arm or central line.
collection of umbilical umbilical cord blood has also become a popular method of collecting stem cells. With this method, stem cells are simply removed from the discarded umbilical cord and the placenta of the newborn during childbirth. The main advantage of this type of stem cell collection is that it does not hurt or discomfort, because the materials would be equally discarded. This trunksVé cells can be frozen for the upcoming transplantation that has already been planned or cryoconzated for any unforeseen needs in the distant future. This method of collecting stem cells has traditionally been reserved for those who donate children or small adults due to the limited number of stem cells available within the umbilical cord and placenta.