What is toxin Clostridium difficile?

Clostridium difficile is a type of bacteria and toxin Clostridium difficile is a substance created by bacteria that affects the lining of the intestine, causing inflammation and damage. Clostridium difficile infection causes anything from mild diarrhea to potentially fatal colon infection with fever, bloody diarrhea and risk of perforated intestine. There are different strains of bacteria and those that produce toxin Clostridium difficile tend to cause more serious diseases. The useful method of testing the disease involves the detection of the presence of toxin Clostridium difficile in the stool sample. Treatment for the condition ranges from nothing, in mild cases, to surgery, if the large intestine or large intestine is in the risk of perforation. When antibiotic are prescribed, these can kill a normal bacterial population in the intestines, allowing clapling Clostridium difficile that usually does not harm antibiotics. Bacteria can then cause intestinal infection and form toxins that create symptoms.

There are two different types of toxin Clostridium difficile, known as A and B, and these can be detected in a stool sample. This provides faster diagnosis than waiting for bacteria in stool sample to identify themselves. Both toxins bind to cells in the intestinal lining and prevent them from functioning normally, causing injury and inflammation.

In some cases, there is only a slight disease with fever, nausea, abdominal cramp and diarrhea of ​​actions. It can usually solve it in itself within a few weeks. Alternatively, it can only be required to stop taking the prescribed antibiotics allow normal intestinal bacteria that inhibit Clostridium difficile to increase again. More serious intestinal diseases occur when a large amount of toxin clostridium difficile is formed and a condition known as pseudomembranous colitis may arise.

pseudomembranous colitis includesIgnition of the large intestine and yellow spots appear on the lining. Fever and abdominal pain usually occur, along with bloody diarrhea and the large intestine can spread. Treatment is generally a short course of one of the specific antibiotics known to affect Clostridium difficile such as vancomycin.

may need to replace the liquid lost due to diarrhea, and this can be done with intravenous drop or by feeding the fluid into the stomach through the nasal tube. Surgery is performed in rare cases where there is a risk that the large intestine can perforate, circumvent or remove the damaged intestine. Clostridium difficile infection can be prevented by good hygineme, to reduce the chance of infection from the surroundings and other people, and avoiding unnecessary antibiotics prescribing.