What is an antigen presentation?

The presentation of the antigen is one aspects of the immune response. In it, the cells of the body spend foreign proteins or antigens into small peptides and express them on their surface. These peptides are built into the cell membranes and are presented by other cells that can generate an immune response. Foreign proteins, such as bacteria and viruses, are primarily to those that are degraded during the antigen presentation.

The immune response is a way to fight the disease. Different types of cells are connected to this answer. Cytotoxic T-lymphocytes are activated to attack and destroy cells infected with virus. Auxiliary T-lymphocytes secrete proteins known as cytokines in activation, and these cytokines hire other cells to the site of infection. In order to be either for cytotoxic T-lymphocytes or auxiliary T-lymphocytes to mount the answer must have foreign antigens presented by other types of cells.

T-lymphocytes have a T-cell receptor on their surface. When T-Bulus receptorK is bound to antigen on the surface of other cells, the T-cell is activated to react. These T-lymphocytes must be able to distinguish foreign pathogens from their own proteins. T-cell can recognize antigen as foreign only when it is associated with the main histocompatible complex (MHC) or its own antigen.

There are two classes of MHC molecules. MHC I Molecules are present on all cells that have a nucleus. MOC I and Class II molecules are present on the surface of specialized cells involved in the antigen presentation. These cells, known as the cells presenting antigen, include dendritic cells, macrophages and B-lymphocytes.

MHC I MOC I cings with endogenous antigens inside the cell. Endogenic antigens, which include viral proteins produced after an infected cell, are then troubled in the cytoplasm into small peptides enzymes. Thepeptides E bind to the MHC class I molecule and are transmittedTo the surface for presentation of cytotoxic T-lymphocytes. Cytotoxic T-lymphocytes can then mount an attack against a cell infected with a virus.

MHC MHC Molecules bind to exogenous antigens that come from the outside of the cell. Exogenous antigens include bacteria and toxins and these antigens are absorbed by the cell presenting the antigen. Once the cells are inside, these antigens are cleaved enzymes and combined with the MHC Class II molecule. This complex is wrapped in vesicles and moves to the cell surface to the auxiliary T-lymphocytes during the presentation of the antigen. These auxiliary T-lymphocytes exclude cytokines that hire other types of cells to the site of infection.