What Is Cerebellar Ataxia?

It is a group of signs of voluntary dyskinesia caused by degeneration of brain tissue mainly in the cerebellum. The disease is hereditary and occurs more frequently than in adulthood. Mainly manifested as ataxia of the extremities, most of the lower limbs are heavier, and may also have nystagmus and bard-like speech. It can be divided into three types: no family history, only cerebellar involvement, and no intentional tremor, which may be cerebellar cortical ataxia; if there is still significant intentional tremor, nystagmus, and late dysphagia, it may be olive, Cerebellar and cerebellar ataxia; if ataxia of the cerebellum, there is obvious intentional tremor, lower limb ataxia or convulsions and myoclonus, it may be cerebellar dentate ataxia. Available treatment with toxic lentiline.

It is a group of signs of voluntary dyskinesia caused by degeneration of brain tissue mainly in the cerebellum. The disease is hereditary and occurs more frequently than in adulthood. Mainly manifested as ataxia of the extremities, most of the lower limbs are heavier, and may also have nystagmus and bard-like speech. It can be divided into three types: no family history, only cerebellar involvement, and no intentional tremor, which may be cerebellar cortical ataxia; if there is still significant intentional tremor, nystagmus, and late dysphagia, it may be olive, Cerebellar and cerebellar ataxia; if ataxia of the cerebellum, there is obvious intentional tremor, lower limb ataxia or convulsions and myoclonus, it may be cerebellar dentate ataxia. Available treatment with toxic lentiline.

Chinese name

Cerebellar ataxia

Foreign name

cerebellar ataxia

Cerebellar ataxia I. Etiology and related diseases

Cerebellar ataxia can be divided into: secondary cerebellar ataxia, hereditary cerebellar ataxia. Secondary cerebellar ataxia is caused by non-hereditary causes. Including idiopathic cerebel-lar ataxia and acquired ataxia with a clear etiology. Causes of acquired ataxia include infection, alcoholism, vitamin deficiency, multiple metabolic diseases, mitochondrial encephalomyopathy, multiple sclerosis, vascular disease, prion disease, primary or metastatic tumors, ovary, breast, or Paracancerous syndrome caused by a latent lung tumor.

Hereditary cerebellar ataxias are classified into autosomal dominant hereditary ataxias, autosomal recessive hereditary cerebellar ataxias, and X-linked cerebellar ataxias. Mainly related to genetic genes.

Cerebellar ataxia 2. Differential diagnosis

Secondary cerebellar ataxia is diagnosed based on the patient's previous cases and related clinical symptoms and related examinations.

Clinical diagnosis of hereditary cerebellar ataxia is difficult. What are the clinical points of view to affirm and type hereditary cerebellar ataxia? This is an important principle for diagnosing hereditary cerebellar ataxia. Nowadays it can be said that the specificity of certain genes from the clinical manifestations is not high, and the possibility is very small. For this reason, Harding's classification method is still important for a clinician.

If the hospital has the technology and equipment, and the patient has the will, further genetic testing should be performed. Genetic diagnosis as a method of clinical auxiliary diagnosis is still difficult to be popularized like EMG and CT, and hereditary cerebellar ataxia is a complex genetic disease. Only in the future when genetic classification diagnosis becomes a routine diagnostic test in hospitals, detailed genetic classification can really provide a basis for diagnosis of cerebellar ataxia.

Cerebellar ataxia III. Principles of treatment

The use of hormones to treat acute cerebellar ataxia, it is believed that short-term application of adrenocortical hormones or intravenous injection of large doses of immunoglobulin can achieve satisfactory results. However, hormones should be used with caution and should not be applied for a long time. The acute phase of the disease can be treated with corticosteroids combined with nutritional nerves, anti-inflammatory and anti-viral therapy, and research has proved that the prognosis is good. Compound Danshen injection combined with hyperbaric oxygen therapy can also be applied; buspirone is a safe and effective drug to improve the symptoms of ataxia. In the clinical application of conventional drug treatment and rehabilitation training, oral buspirone was added, and studies have shown that patients have significantly improved balance and coordination.