What is Glucocorticoid?

Glucocorticoid (GC) is a very important class of regulatory molecules in the body. It plays an important role in regulating the body's development, growth, metabolism, and immune function. It is the most important regulatory hormone in the body's stress response. It is also clinical The most widely used and effective anti-inflammatory and immunosuppressant. In emergency or critical situations, glucocorticoids are often preferred. Commonly used glucocorticoids are prednisone, methylprednisolone, betamethasone, beclomethasone propionate, depotamone, prednisone, hydrocortisone, and dexamethasone. With anti-inflammatory, anti-toxic, anti-allergic, anti-shock, non-specific suppression of immune and antipyretic effects, can prevent and prevent the occurrence of immune inflammatory reactions and pathological immune reactions, to any type of allergic diseases Almost all works.

Basic Information

Application of glucocorticoids

In the treatment of primary or secondary (pituitary) adrenal insufficiency, physiological doses of hydrocortisone or cortisone are supplemented or replaced. It can also be used for various allergic diseases, such as angioedema, acute urticaria, contact dermatitis, serum disease, anaphylactic shock, severe blood transfusion reaction, thrombocytopenic purpura, severe bronchial asthma, etc.

Glucocorticoid adverse reactions

Although this product is effective for the relief of acute symptoms, if it is used for a long time, its adverse reactions cannot be ignored. Common adverse reactions:

1. Disorders of water, salt, sugar, protein and fat metabolism: manifested as concentric obesity (Cushing's syndrome), full moon face, buffalo back, acne, hairy, high sodium and hypokalemia, hypertension, edema, Hyperlipidemia, hyperglycemia or exacerbation of diabetes, impaired adrenal function, or even atrophy, amenorrhea, muscle wasting, weakness, osteoporosis, femoral head necrosis and mental symptoms.

2. Reduce body resistance.

3. Impede tissue repair and delay tissue healing.

4. Inhibit children's growth and development.

Glucocorticoids considerations

Large doses of glucocorticoids should not be pregnant. Pregnant women use glucocorticoids with caution. The use of physiological or maintenance doses of glucocorticoids in lactating women generally has no significant adverse effects on infants. However, breastfeeding women should not breastfeed when receiving glucocorticoids in a medium-dose, medium-term treatment regimen to avoid the adverse effects of glucocorticoids secreted by milk on infants. Long-term use of glucocorticoids in children should pay close attention to adverse reactions to avoid or reduce the effects of glucocorticoids on the growth and development of children. Elderly patients using this product and other glucocorticoids are prone to hypertension and osteoporosis, and women after menopause are prone to osteoporosis.

(Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.)