What is haemostasis?
Hemostasis is a process by which blood turns into a solid condition. This is what stops bleeding after blood vessel damage. Blood vessels are protected by cells that prevent the formation of thrombin, a coagulation protein that catalyzes the reactions in the bloodstream. When the injury penetrates the cells and reaches the blood vessels, haemostasis occurs.
There are two haemostasis phases. During the first, primary haemostasis, the vascular muscle contracts are temporarily downloaded as soon as the cells are disturbed. This contraction slows the blood flow and either activates or accelerates the adhesion of platelet. During the adhesion, the proteins on the surface of each plate of the rods on the von Willebrand factor, the protein found in the blood plasma.
When the plates are collected on the surface, they establish contact with collagen, the main proteins in humans and are therefore activated. These plates obscure the surface and fibers and receptors of the diaphragm of the plates grab the fibrinogen, the protein found in the plasma and synthesized by the liver. When plates and fibrinogen accumulateČKU. All this happens within 20 seconds after the injury.
During secondary haemostasis, the clot is stabilized, but the secretion of the plates continue in the contractions of the vascular muscle. Through the interaction of enzymes, plates and various coagulation processes, the plug becomes solid. Coagulation processes occur in the liver, but do not actively circulate throughout the body until something called a coagulation cascade begins. Throughout the cascade, there are a number of steps in which one reaction leads to the other until the fibrinogen is converted to fibrin, a protein that forms a haemostatic plug or a clot above the injury. Fibrin is first in the texture, but when plates and red blood cells are combined with dense grouping of fibers, a blood clot is formed.
Henejstvě and thrombosis are closely linked because thrombosis is the formation of a blood clot in a blood vessel. Thrombosis may occur in a vein or artery and the precipitate itselfIt calls thrombus , which is Greek for lump or cluster. Trombosis in the vein can cause deep venous thrombosis, a condition that affects blood clotting in the legs. Coronary thrombosis is a thrombosis that affects arteries and can cause a heart attack when a blood clot cut off the blood supply to the heart. Thrombus may be caused by damage to blood vessels, disruption of regular blood flow, inflammation or atherosclerosis.