What is the connection between nicotine and dopamine?

Dopamine is a neurotransmitter responsible for feelings such as pleasure, relaxation and happiness. Nicotine affects almost every part of the human body, especially the brain. When nicotine and dopamine receptors interact, the brain changes how dopamine creates and responds to dopamine. This reaction is the primary cause of nicotine dependence. While the average cigarette contains only 1 mg to 3 mg nicotine, it is sufficient to cause a long -term change in the human brain. Nicotine causes the brain to produce more dopamine than usual, which is responsible for the stimulating and euphoric effects of tobacco use. The effect on the levels of dopamine in the brain is a similar effect that has amphetamines and psychostimulants on the brain, so the use of tobacco is comparable to the use of drugs such as cocaine.

when nicotine and dopamine receptors interact and the brain of the beginning produces more dopamine in response to nicotine, causing the brain to reduce its production of natural dopamine. The organization basically learns that this neurOtransmitter only create in response to the drug than in response to its natural function. Although this process occurs quite quickly, it continues long after the use of nicotine stops, which represents a number of tobacco users who have stopped custom just to return to it for months or years later.

nicotine and dopamine play a trick on the human brain. When nicotine is first introduced into the body, while the brain still produces dopamine naturally, it causes the brain to produce a much higher level of dopamine than used for production. This, in turn, causes the brain to create more dopamine receptors to handle the amount of dopamine produced, causing the brain more sensitive to nicotine and dopamine presence and their absence.

nicotine and dopamine are combined, are the primary reason for dependence on tobacco products and withdrawal symptoms associated with ending. Changing the brain to the production of dopaMIN in certain situations and the increase in dopamine receptors makes those who use tobacco products need frequent and stable "repairs" to feel normal. This, associated with the fact that nicotine usually wear the effects of nicotine within minutes, is the primary reason why the termination of tobacco products is so difficult.