What is the connection between telomerase and aging?
telomerase is an enzyme produced by the body that slows the process of aging at the molecular level by rebuilding DNA bits at the ends of chromosomes called telomers. During each cell division, telomers protect and help chromosome, which cannot be divided to its end. Telomers also reduce slightly every time the cell is divided, while the activity of telomerase extends and rebuilds telomeres. Without telomerase, the cell can divide the final number of times before it "ages" and dies as a result of shortening its telomers. The discovery of this process has supported the hope that research of telomerase and aging can bring ways to delay or reverse the process of aging human and its related diseases and disorders. aging. Mice that made notes produces telomerase twice as fast as mice that had normal levels. When their telomerase was activated, all signs of aging reversed, while the brain and organs normally regenerate and operate.
The results of this research were explained by one of the reasons why people age. The connection between telomerase and aging was reinforced when it was found that people who were born with premature aging disorders have short telomers. The mutation of the telomerase subunit gene was associated with various diseases and disorders such as aplastic anemia and other bone marrow diseases. Other studies have found that cells taken from people at the age of twenty are divided several times before death than cells from elderly. Other studies couldn't back up.
Aging is a complex process controlled by interaction of the amount of mechanisms. Many scientists say it is too early to apply what is known about telomerase and aging people, because most of the research was performed only in mice. Another potential problem is the role of telomerase in cancer.
cancer cells tend to have shorter telomers and higher levels of telomerase that increase their growth. Introduction of TestomerAnti -aging therapy could be disastrous if the person did not detect cancer. Telomerase is one of the reasons why cancer cells grow from control, in fact become immortal. Some scientists suggest that people have a limited amount of telomerase to protect against cancer. Increasing levels could not only reduce aging speed, but also stimulate cancer growth.
The connection between telomerase and aging seems to be more complicated than originally thought. While telomerase has a certain relationship to the speed that cells and the whole organism are aging, it is not the only factor in work. Scientists still cannot tell from Telomers how old the host could be due to many processing involved in aging.