Is it safe to combine clopidogrel inhibitors and proton pump?

Clopidogrel is commonly used to prevent precipitation clotting in patients with high risk of heart attacks or strokes. Proton pump inhibitors belong to the class of drugs aimed at reducing stomach acid production. People with gastrointestinal ulcers or gastroesophageal reflux disease (GERD) can benefit from using proton pump inhibitors. Anti -aggregation drugs can cause gastrointestinal side effects and patients can be instructed to take medicines such as clopidogrel inhibitors and proton pumps together. However, the current use of these two significantly reduces the efficiency of clopidogrel and is therefore not recommended.

anti -aggregation drugs usually inhibit the formation of arterial blood clots. People with atherosclerosis usually use clopidogrel as part of the treatment plan to prevent the formation of a clot. The drug can also be used to prevent further clothed events in patients who have already suffered a heart attack or stroke. Like all Medications, KLOpidogrel has some side effects, including allergic reactions and fatigue. The use of clopidogrel can also cause gastrointestinal problems such as diarrhea, stomach pain, ulcers and bleeding.

Proton pump inhibitors have a direct effect on acid -producing cells that form stomach lining. The use of such drugs generally reduces the production of acid in the stomach. This usually supports the healing of existing stomach ulcers. Reduction of stomach acids can also help improve symptoms in patients with GERD. When combining clibers and proton pump inhibitors, gastrointestinal side effects associated with anti -aggregation drugs can reduce gastrointestinal side effects.

Clopidogrel is inactive when removing and is converted to the active form of the enzyme in the body. Proton pump inhibitors can disrupt this process by blocking the clopidogrel to its active form. Smowitant use of inhibitors KLOPidogrel and proton pump may result in the concentration of clopidogrel in the blood, which is significantly below therapeutic levels. This can have serious consequences. Reduction of the drug may result in breakthrough precipitation.

Medical studies suggest that concurrent use of clopidogrel and proton pump inhibitors is not safe. People should avoid using these two drugs to obtain the full therapeutic effect of clopidogrel therapy. Current income may result in serious complications due to reduced clopidogrel efficiency.