What are the advantages and disadvantages of NSAID and PPI?

Many patients suffering from arthritis pain and other chronic conditions take regular doses of non -steroidal anti -inflammatory drugs (NSAIDs) such as aspirin, naproxen and ibuprofen. Although these drugs can help alleviate pain and inflammation, long -term use may lead to damage to the stomach lining and intestinal tract. To combat this risk, NSAIDs can be combined with the class of medicines known as protein pump inhibitors (PPI). These drugs help reduce the amount of acid produced in the stomach and reduce damage caused by long -term use of NSAIDs. PPIs have their own side of side effects, including the increased risk of hip fractures, so it is important to consult a doctor to discuss the advantages and disadvantages of this treatment before using NSAIDs and PPIs in combination.

NSAIDs, such as Aspirin, are among the most commonly used drugs and are recommended for various disease injuries. Patients suffering from arthritis or, toTears are at risk of brain or infarction caused by the formation of a clot, often take NSAIDs for a long time to help treat these health conditions. NSAID is the only class of drugs capable of suppressing the enzyme cyclooxygenase known as COX-1, which is responsible for inflammation in the human body. This COX-1 enzyme also helps to produce compounds that protect the lining of the stomach and intestines from digestive acid. NSAIDs can also damage the lining of the gastrointestinal tract directly, adying drug research workers to consider the administration of NSAIDs and PPI in combination.

While there are several categories of drugs that can help reduce stomach acid and promote NSAID damage, PPI were the most effective treatment for many patients. Using NSAIDs and PPI in combination may have less gastrointestinal side effects, including ulcers and sour reflux diseases. Make NSAID and PPI patients separately or receive a prescription for both drugs in one pill or tablet.

patientsThey use PPIs are threatened by a number of minor side effects and some more serious side effects. One of the remarkable side effects is the increased risk of hip and other bone fractures. This is a bigger problem for elderly patients who can already have weak bones due to osteoporosis or osteoarthritis. Patients considering long -term use of NSAIDs and PPI should speak to their primary care doctor for the advantages and disadvantages of each of these drugs before the start of the treatment regimen.